國立清華大學材料工程學系

Members

:::

Name	TZU-WEI WANG
Current Phone No.	#33856 (Lab:31165, 33846)
FAX No.
Current Address	Delta Building R434, National Tsing Hua University
E-mail
E-mail(2)
Personal Website	http://sites.google.com/site/teamtwlab

Classification	Full-Time
Title	Assistant Professor
Discipline	-Biomedical Materials -Principles of Human Physiology -Tissue Engineering & Regenerative Medicine -Nanomedicine for Biomedical Application
Speciality	-Novel Functionalized Smart Biomaterials -Stem Cells & Tissue Engineering & Drug Delivery -Nanomedicine for Diagnosis and Therapeutics

Publication List

1. Journal Articles
   1. Yu-Ju Chang, Cho-Jen Tsai, Fan-Gang Tseng, Tsung-Ju Chen, Tzu-Wei Wang*., "Micropatterned Stretching System for the Investigation of Mechanical Tension on Neural Stem Cells Behavior." , Nanomedicine: Nanotechnology, Biology, and Medicine (accepted in press), 2013
   2. Goh Jih Her, Hsi-Chin Wu, Ming-Hong Chen, Ming-Yi Chen, Shun-Chih Chang, Tzu-Wei Wang*., "Control of three-dimensional substrate stiffness to manipulate mesenchymal stem cell fate toward neuronal or glial lineages." , Acta Biomaterialia 2013;9(2):5170-5180, 2013
   3. Tzu-Yun Cheng, Ming-Hong Chen, Wen-Han Chang, Ming-Yuan Huang, Tzu-Wei Wang*., "Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering" , Biomaterials 2013; 34(8):2005-2016, 2013
   4. Tzu-Yun Cheng, Wen-Han Chang, Ming-Yuan Huang, Chao-Hsiung Lee, Tzu-Wei Wang*., "Functionalized Self-Assembling Nanopeptides for Immediate Hemostasis and Accelerative Liver Tissue Regeneration." , Nanoscale (accepted in press), 2013
   5. Ying-Yu Chen, Hsi-Chin Wu, Jui-Sheng Sun, Guo-Chung Dong, Tzu-Wei Wang*., "Thermoresponsive and injectable pluronic F127/hyaluronic acid nanocomposite hydrogel system for anti-cancer drug delivery." , Langmuir (accepted in press), 2013
   6. Yu-Jie Huang, Hsi-Chin Wu, Nyan-Hwa Tai, Tzu-Wei Wang*., "Carbon Nanotube Rope with Electrical Stimulation Promotes the Differentiation and Maturity of Neural Stem Cells." , Small 2012;8(18): 2869–2877 , 2012
   7. Yeh PH, Wu HC, Sun JS, Wang TW*., "Development of disulfide-modified hyaluronan graft polyethyleneimine nanocarrier for gene transfection." , Journal of Tissue Engineering and Regenerative Medicine 2012; 6(S1): 288, 2012
   8. Wu HC*, Tsai ZR, Wang TW, Sun JS, Shen MH, Wang YC., "Characterization of enzymatic crosslinked hydroxyapatite/collagen nanocomposite for bone tissue engineering." , Journal of Tissue Engineering and Regenerative Medicine 2012; 6(S1): 196-197, 2012
   9. Wu HC, Wang TW, Lin FH, Sun JS*., "Characterization of Magnetic Hydroxyapatite Nanocrystallites and Potential Application for MRI Contrast Agent. " , Current Nanoscience 2011;7:902-907, 2011
   10. Wu HC, Wang TW, Bohn MC, Lin FH *., "Evaluation of Magnetic-Hydroxyapatite Nanoparticles for Gene Delivery Carrier." , Biomedical Engineering-Applications, Basis & Communications.2010; 22(1):33-39, 2010
   11. Wu HC, Wang TW, Bohn MC, Lin FH, Spector M*., "Novel Magnetic Hydroxyapatite Nanoparticles as Non-viral Vectors for the Glial Cell-line Derived Neurotrophic Factor Gene. " , Advanced Functional Materials 2010;20(1):67-77, 2010
   12. Wang TW, Wu HC, Wang HY, Tsuang YH, Lin FH*, Sun JS*. , "Regulation of Adult Human Mesenchymal Stem Cells into Osteogenic and Chondrogenic Lineages by Different Bioreactor System" , Journal of Biomedical Materials Research Part A. 2009;88(4):935-46, 2009
   13. Wang TW, Spector M*. , "Development of hyaluronic acid-based scaffolds for brain tissue engineering" , Acta Biomaterialia. 2009:5(7):2371-2384, 2009
   14. Wang TW, Lu HY, Lou FH*., "Application of Highly Sensitive, Modified Glass Substrate based Immino-PCR on the Early Detection of Nasopharyngeal Carcinoma" , Biomaterials. 2008;29(33):4447-54, 2008
   15. Tseng CL, Wang TW, Dong GC, Wu YH, Lin FH*., "Surface Modification of Gelatin Nanoparticles with Biotinylated-EGF for Lung Cancer Targeting" , Biomaterials. 2007:28(27):3996-4005, 2007
   16. Wang TW, Wu HC, Wang WR, Lin FH*, Lou PJ, Shieh MJ, Young TH., "The Development of Magnetic Degradable DP-Bioglass for Hyperthermia Cancer Therapy" , Journal of Biomedical Materials Research Part A.2007;83(3):828-837, 2007
   17. Wu HC, Wang TW, Sun JS, Wang WH, Lin FH*. , "A Novel Biomagnetic Nanoparticle Based on Hydroxyapatite" , Nanotechnology.2007;18:165601, 2007
   18. Wang TW, Sun JS, Wu HC, Lin FH*., "Evaluation and Biological Characterization of Bi-layer Gelatin/Chondroitin-6Sulphate/Hyaluronic Acid Membrane" , Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2007:82(2):390-9, 2007
   19. Wu HC, Wang TW, Kang PL,Tsuang YH, Sun JS*, Lin FH*. , "Coculture of Endothelial and Smooth Muscle Cells on a Collagen Membrane in the Development of a Small-diameter Vascular Graft" , Biomaterials.2007;28(7):1385-1392, 2007
   20. Wang TW, Wu HC, Sun JS, Lin FH*., "Real-time PCR Quantification of Protein Expression in Skin Equivalent Monoculture and Coculture Model" , Advanced Materials Research. 2007; 15-17: 101-106, 2007
   21. Wang TW, Wu HC, Sun JS, Lin FH*., "Real-time PCR Quantification of Protein Expression in Skin Equivalent Monoculture and Coculture Model." , Advanced Materials Research. 2007; 15-17: 95-100, 2007
   22. Wang TW, Wu HC, Huang YC, Sun JS, Lin FH*., "The Effect of the Self-designed Bifunctional RGD-containing Fusion Protein on the Behavior of Human Keriocytes and Dermal Fibroblasts" , Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2006 ;79(2):379-87, 2006
   23. Wang TW, Sun JS, Wu HC, Tsuang YH, Wang WH, Lin FH*., "The Effect of Gelatin-Chondroitin Sulphate-Hyaluronic Acid Skin Substitute on Wound Healing in SCID Mice" , Biomaterials. 2006 ; 27(33):5689-97, 2006
   24. Wang TW, Sun JS, Huang YC, Wu HC, Chen LT, Lin FH*., "Skin Basement Membrane and Extracellular Matrix Protines Characterization and Quantification by Real Time RT-PCR" , Biomaterials. 2006;27(29):5059-5068, 2006
   25. Wang TW, Wu HC, Huang YC, Sun JS, Lin FH*., "Biomimetic Bi-layered Gelatin-Chondroitin 6 Sulphate-Hyaluronic Acid Biopolymer AS the Scaffold for Skin Equivalent Tissue Engineering" , Artificial Organs. 2006;30(3):141-149, 2006
   26. Huang YC, Wang TW, Sun JS, Lin FH*., "The Investigation of MMC-treated Fibroblast in3-D Collagen Gel and Conditioned Medium for Kertinocyte Proliferation" , Artificial Organs. 2006;30(3):150-159, 2006
   27. Wang TW, Wu HC, Huang YC, Sun JS, Lin FH*., "Preparation and Evaluation of GAG-incorporated Skin Substitute: An In Vitro Study" , Biomedical Engineering-Applications, Basis & Communications. 2006;18:153-157, 2006
   28. Huang YC, Wang TW, Sun JS, Lin FH*., "Effect of Calcium Ion Concentration on Kertinocyte Behaviors in the Defined Media" , Biomedical Engineering-Applications, Basis & Communications. 2006;18:37-41, 2006
   29. Huang YC, Wang TW, Sun JS, Lin FH*., "Epidermal morphogenesis in an in-vitro model using a fibroblasts-embedded collagen scaffold." , Journal of Biomedical Science. 2005;12(6):855-867, 2005
   30. Wang TW, Huang YC, Sun JS, Lin FH*., "Organotypic Keratinocyte-fibroblast Cocultures on a Bilyaer Gelatin Scaffold as a Model of Skin Equivalent" , Biomedical Sciences Instrumentation. 2003;39: 523-528, 2003
   31. Huang YC, Wang TW, Sun JS, Lin FH*. , "Cultured Keratinocytes and Dermal Fibroblasts on a Double-layer Scaffold with Bi-medium Culture System" , Biomedical Sciences Instrumentation. 2003;39: 500-505, 2003
   32. Wu HC, Wang TW, Lin FH, Sun JS, " Characterization of Magnetic Hydroxyapatite Nanocrystallites and Potential Application for MRI Contrast Agent" , Current Nanoscience (in press) ,
2. Patent
   1. Wang TW, Huang YC, Lin FH, "Biocompatible Bilayer Porous Matric and Preparation" , Taiwan Patent 368653 , 2012
   2. Wu HC, Lin FH, Wang TW, "Magnetic Nanoparticles of Hydroxyapatite and Preparation Method Thereof" , Taiwan Patent 375567, 2012
   3. Wu HC, Lin FH, Wang TW, "Magnetic ceramic nanocrystallite as non-viral gene vector and preparation for gene therapy in biomedical applications" , Taiwan Patent 379689, 2012
   4. Lu HY, Wang TW, Lin FH, "Immuno-PCR Method for Detecting Nasopharyngeal Carcinoma Barkers and Kit" , USA Pat. 7807347 , 2010
   5. Wang TW, Lin FH, "Cell Culture Device" , USA Patent 12314631 - Filed 15 Dec 2008, 2008
   6. Wu HC, Lin FH, Wang TW, "Magnetic Nanoparticles of Hydroxyapatite and Preparation Method Thereof" , US Pat. 11956400 - Filed Dec 14, 2007, 2007
   7. Lin CH, Wang TW, "Protein For Improving Cell-Attachment Efficiency and Use Thereof" , USA Pat. 11552507 - Filed Oct 24, 2006 , 2006

Research ProjectOverview

Year	Project Name	Participator	Job	Period	Cooperative Organization	Remarks
2012	Self- Assembling Peptide in the Treatment of Brain Hemorrhage and Neural Regeneration.	TZU-WEI WANG	PI	2012-01 ~ 2012-12	NTHU-Mackay Memorial Hospital Joint Research Program
2012	Neural Stem Cells Mediated Nanopeptide Hydrogel for Brain Tissue Engineering.	TZU-WEI WANG	PI	2012-01 ~ 2012-12	NTHU-National Taiwan University Hospital Hsinchu Branch Research Program
2011	Neurogenic potential of human umbilical cord blood stem cells on 3D biomimetic scaffold and tissue engineering applications.	TZU-WEI WANG	PI	2011-01 ~ 2011-12	NTHU-Chang Gung Memorial Hospital Joint Research Program
2011	Peptide nanofiber scaffold for brain repair and wound healing effect.	TZU-WEI WANG	PI	2011-01 ~ 2011-12	NTHU-Mackay Memorial Hospital Joint Research Program
2011	Development of novel thermo-responsive biodegradable, injectable hydrogel and its applications.	TZU-WEI WANG	PI	2011-08 ~ 2014-07	National Science Council
2010	Rapidly curable gelatin/fibrin glue incorporated with self-assembling nanopeptides in traumatic hemostasis and burn management	TZU-WEI WANG	PI	2010-01 ~ 2010-12	NTHU-Mackay Memorial Hospital Joint Research Program
2010	Novel injectable hydrogel as biodegradable scaffold and cell delivery vehicle	TZU-WEI WANG	PI	2010-01 ~ 2010-12	NTHU Boost Program
2010	Endostatin gene transfected mesenchymal stem cells for the treatment of osteoarthritis	TZU-WEI WANG	PI	2010-01 ~ 2010-12	NTHU-National Taiwan University Hospital Hsinchu Branch Joint Research Program
2010	Investigation of Stem Cell Therapy in Brain Tissue Engineering Using Novel 3D Hyaluronan-based Biomatrices	TZU-WEI WANG	PI	2010-08 ~ 2013-07	National Science Council
2009	Functionalized carbon nanotubes as delivery carrier/tracer, electrode, and matrix enhancement in the biomedical applications	TZU-WEI WANG	PI	2009-07 ~ 2011-07	National Science Council
2009	Electrospun fibrin/hyaluronan nanofiber with anti-bacteria silver nanoparticle as a novel wound dressing	TZU-WEI WANG	PI	2009-07 ~ 2010-06	National Science Council

Industry-Academy CooperationOverview

Year	Project Name	Participator	Job	Period	Cooperative Organization	Remarks
2009	利用電紡技術製備具抗菌性纖維蛋白與透明質酸奈米絲作為新式人工皮膚創傷敷料	TZU-WEI WANG	Manager	2009-07 ~ 2010-06	潤霈生技股份有限公司

Work Experience

Institution	Title	Department/Division	Job Position	Date
Harvard Medical School, USA	Postdoctoral Research Fellow	VA Boston Healthcare System and the Department of Orthopaedic Surgery of the Brigham and Women's Hospital		2007-09 ~ 2009-02
National Taiwan University	Postdoctoral Research Fellow	Institute of Biomedical Engineering		2006-08 ~ 2007-07

Outside School HonorOverview

得獎年度	獎項名稱	頒獎單位
2012	Excellent Poster Paper Award	Annual Symposium on Biomedical Engineering and Technology (BME2012)
2012	The 9th National Innovation Award in the Academic Research Category	Institute for Biotechnology and Medicine Industry, Taiwan (2012)
2012	The Best Poster Award	2012 International Symposium of Materials on Regenerative Medicine (2012 ISOMRM)
2012	Young Investigator Awards (co-author research work)	2012 International Symposium of Materials on Regenerative Medicine (2012 ISOMRM)
2011	Young Investigator Awards (co-author research work)	5th World Congress on Bioengineering, the World Association for Chinese Biomedical Engineers, Taiwan (WACBE 2011)
2011	Best Paper Award	Annual Symposium on Biomedical Engineering and Technology, Taiwan (BMES 2011)
2010	Excellent Poster Paper Award	Materials Research Society-Taiwan Annual Conference, 2010 (MRS-T)
2008	Taiwan Merit Postdoctoral Fellowship	National Science Council
2007	Postdoctoral Fellowship	Yen Tjin Ling Industrial Development Foundation, NTU
2007	Excellent Graduate Research Paper Award	NTU College of Medicine
2007	Postdoctoral Fellowship	NTU
2006	The 4th Place Award	Taiwan Competition on Biomedical Engineering Creative Designs
2006	Outstanding Students Conference Travel Grant	Foundation for the Advancement of Outstanding Scholarship
2006	The Best Oral Paper Award	Formosa Association of Regenerative Medicine Annual Symposium
2006	The 2nd Place Award	The Fourth National Innovation Award-Student Research Contest by Institute for Biotechnology and Medicine Industry
2005	The 2nd Place Award	The Third National Innovation Aware-Student Research Contest by Institute for Biotechnology and Medicine Industry
2003	The 3rd Place Poster Paper Award	The Chinese Society for Materials Science 2003 Annual Symposium
2003	The Best Oral Paper Award	Biomedical Engineering Society 2003 Annual Symposium
2003	The 2nd Place Paper Award	Rocky Mountain Bioengineering Symposium, Biloxi, Mississippi, USA

Education

University	Nation	Department	Diploma	Date
National Taiwan University	Taiwan	Institute of Biomedical Engineering	Ph. D.	2001-09 ~ 2006-06

ResearchOverview

Title	Date	Attach File
Novel Functionalized Smart Biomaterials: Development and Applications in Tissue Engineering and Drug Delivery
Manipulation of Stem Cell Fate: Control of Extracellular Microenvironment Using Physical, Chemical, and Biological Approaches

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National Tsing Hua University
Department of Materials Science and Engineering,
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TEL：886-3-5715131 ext 33830,33831  FAX：886-3-5722366
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